Modified Brainstem Auditory Evoked Responses in Patients with Non-brainstem Compressive Cerebral Lesions

Autor: Prasad Vannemreddy, John J. Fino, Fady T. Charbel, James L. Stone
Rok vydání: 2012
Předmět:
Zdroj: Acta Neurochirurgica Supplementum ISBN: 9783709109557
DOI: 10.1007/978-3-7091-0956-4_14
Popis: The brainstem auditory evoked response (BAER) is sensitive to pontomesencephalic integrity, transtentorial brain herniation, and at times increased intracranial pressure (ICP). The authors report their experience utilizing a recently described rapid rate, binaural, click and 1,000-Hz tone-burst modification of the BAER (MBAER) in 22 symptomatic non-trauma patients with non-brainstem compressive space-taking cerebral lesions. The majority presented with mild to moderate clinical signs suggestive of increased ICP, and focal neurological deficits. The cerebral lesions, mostly tumors (17), averaged 4–5 cm in diameter, with radiological signs of mass effect such as flattening of the sulci, midline shift, and narrowing of the basal cisterns. A number of significant changes in Wave V and V n latency and less so amplitude were found in patients compared with age-matched normal volunteers, as well as those again studied after surgical decompression. Similar MBAER changes had been noted in normal volunteers placed in a dependent head position. Possible mechanisms to explain these findings are discussed. The methodology shows promise and if combined with automated peak recognition could make Neuro ICU monitoring practical.
Databáze: OpenAIRE