Evaluation of neutrophil–lymphocyte ratio and platelet–lymphocyte ratio as markers of diabetic kidney disease in Bangladeshi patients with type 2 diabetes mellitus
| Autor: | P K Chanda, Marufa Mustari, Mohammad Abdul Hannan, Farhana Akter, Abu Jar Gaffar, Shahjada Selim, A Bm Kamrul-Hasan, Mohammad Saifuddin, Mohammad Motiur Rahman, Asaduzzaman |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test Mean corpuscular hemoglobin concentration business.industry Mean corpuscular hemoglobin Renal function Complete blood count Red blood cell distribution width Gastroenterology chemistry.chemical_compound chemistry Internal medicine medicine Absolute neutrophil count General Earth and Planetary Sciences Glycated hemoglobin business Mean corpuscular volume General Environmental Science |
| Zdroj: | Journal of Diabetology. 12:58 |
| ISSN: | 2078-7685 |
| DOI: | 10.4103/jod.jod_4_20 |
| Popis: | Background: The roles of neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) as novel surrogate markers of diabetic kidney disease (DKD) are promising. Objective: The aim of this study was to evaluate whether NLR and PLR can predict DKD in type 2 diabetes mellitus (T2DM). Subjects and Methods: This cross‑sectional study was conducted from July 2018 to June 2019, among 312 patients with T2DM recruited from eight tertiary hospitals throughout Bangladesh. Complete blood count (CBC) was performed in fully automated hematology analyzers, and NLR and PLR were calculated. The urine albumin-to-creatinine ratio (ACR) was measured in a random single-voided urine sample. The diagnosis of DKD was made based on the presence of albuminuria (ACR ≥30 mg/g) and/or reduced estimated glomerular filtration rate (eGFR |
| Databáze: | OpenAIRE |
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