Topical Vitamin A Acid (Airol®) and Systemic Oxytetracycline in the Treatment of Acne Vulgaris
Autor: | Wehnert R, A. Nørholm, Aastrup B, N P Rosman, Per Holm, Reiter H, E. Gadborg, Flemming Reymann, K. Ludvigsen, P. Unna, Jørgen Christiansen, Rasmussen Ka, Andersen B, Konstman Meier Ch, Pedersen D, Sylvest B, Osmundsen Pe |
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Rok vydání: | 1974 |
Předmět: | |
Zdroj: | Dermatology. 149:121-128 |
ISSN: | 1421-9832 1018-8665 |
Popis: | A double-blind, controlled multi-centre trial with 238 patients was employed to study the relative merits of three treatment schedules in acne vulgaris. Schedule A consisted of oral oxytetracycline and topical vitamin A acid cream (0.05%), schedule B of oral oxytetracycline alone, and schedule C of vitamin A acid alone. Large and statistically significant reductions occurred in the number of come dones, papules and pustules during 8 weeks of therapy, which could be attributed neitherto placebo effects nor to natural history of the disease. |
Databáze: | OpenAIRE |
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