Topical Vitamin A Acid (Airol®) and Systemic Oxytetracycline in the Treatment of Acne Vulgaris

Autor:	Wehnert R, A. Nørholm, Aastrup B, N P Rosman, Per Holm, Reiter H, E. Gadborg, Flemming Reymann, K. Ludvigsen, P. Unna, Jørgen Christiansen, Rasmussen Ka, Andersen B, Konstman Meier Ch, Pedersen D, Sylvest B, Osmundsen Pe
Rok vydání:	1974
Předmět:	medicine.medical_specialty Schedule Erythema business.industry Dermatology Oxytetracycline Vitamin a acid medicine.disease law.invention Clinical trial Randomized controlled trial Tretinoin law medicine medicine.symptom business Acne medicine.drug
Zdroj:	Dermatology. 149:121-128
ISSN:	1421-9832 1018-8665
Popis:	A double-blind, controlled multi-centre trial with 238 patients was employed to study the relative merits of three treatment schedules in acne vulgaris. Schedule A consisted of oral oxytetracycline and topical vitamin A acid cream (0.05%), schedule B of oral oxytetracycline alone, and schedule C of vitamin A acid alone. Large and statistically significant reductions occurred in the number of come dones, papules and pustules during 8 weeks of therapy, which could be attributed neitherto placebo effects nor to natural history of the disease.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9e603da215b6450c65c8b98139056db3 https://doi.org/10.1159/000251498 Zobrazit plný text záznamu