A Comparison of MRI Scoring Systems Predictive Ability for Two-Year Neurodevelopmental Outcome in Neonatal Encephalopathy

Autor: Marie Slevin, Tim Hurley, Arun L.W. Bokde, Deirdre Sweetman, Eleanor J. Molloy, Saima Aslam, Angela T. Byrne, John Murphy, Gabrielle C. Colleran, Megan Ní Bhroin, Lynne Kelly
Rok vydání: 2021
Předmět:
Zdroj: SSRN Electronic Journal.
ISSN: 1556-5068
Popis: Background: MRI scoring systems are used in the perinatal period to predict later neurodevelopmental outcome in infants with neonatal encephalopathy (NE). Our objective was to compare the predictive ability of 3 MRI scoring systems for neurodevelopmental outcome at 2 years of age in infants with NE. Methods: We retrospectively analysed MRI scans from term-born neonates with NE in the first two weeks of life between February 2011 and June 2015 using three scoring systems: Barkovich, NICHD-NRN and Weeke. Neurodevelopmental outcome was assessed using Bayley Scales of Infant and Toddler Development, third edition (Bayley-III) 2 years later. After adjusting for postmenstrual age at MRI scan and therapeutic hypothermia, the relationship between scoring systems and Bayley-III composite scores was assessed by regression analysis and logistic regression was used to calculate the predictive value of MRI scoring systems for adverse outcome (Bayley-III score of
Databáze: OpenAIRE