Flow Injection Chemiluminescence Sensor with Novel Rhodanine Ramification for Determination of Fenfluramine Based on Molecularly Imprinted Polymer
| Autor: | Ge Shenguang, Dai Ping, Li Bo, Yu Jinghua, Huang Jia-dong, Wan Fu-wei |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Flow injection analysis
Chromatography Chemistry Ethylene glycol dimethacrylate Biochemistry (medical) Clinical Biochemistry Molecularly imprinted polymer Biochemistry Analytical Chemistry law.invention chemistry.chemical_compound Potassium permanganate Rhodanine law Reagent Electrochemistry Ethylene glycol Spectroscopy Chemiluminescence |
| Zdroj: | Analytical Letters. 42:746-757 |
| ISSN: | 1532-236X 0003-2719 |
| DOI: | 10.1080/00032710902722004 |
| Popis: | Flow injection chemiluminescence (FI-CL) with molecularly imprinted polymer (MIP) was applied to determine fenfluramine. The fenfluramine-imprinted polymer was prepared with acrylamide (AM) as functional monomer and ethylene glycol dimethacrylate (EGDMA) as cross-linker. Methyl and sulfonic group were introduced to rhodanine matrix, and a novel rhodanine ramification 3MORASP was synthesized by the author, and it was used as chemiluminescence reagent. 3-(3′-Methoxyphenyl)-5(2′-sulfonylphenylazo)-rhodanine (3MORASP), first synthesized by the authors, was used as chemiluminescence (CL) reagent. The novel flow path of FI-CL was designed, which made three merged streams of reactants injected into MIP column move through different pathways simultaneously. Fenfluramine was detected based on the reaction of fenfluramine, 3MORASP, and potassium permanganate in an acidic medium. The CL intensity was correlated linearly with the concentration of fenfluramine over the range of 1.0 × 10−7 to 5.0 × 10−6 g · mL... |
| Databáze: | OpenAIRE |
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