DOFETILIDE ASSOCIATED QT PROLONGATION: ACTUAL VERSUS IDEAL BODY WEIGHT TO CALCULATE DOSING

Autor: Stephen Wang, Robert W Maloney, Terrence D. Welch, Rajbir S. Sangha, Aaron V. Kaplan
Rok vydání: 2017
Předmět:
Zdroj: Journal of the American College of Cardiology. 69:401
ISSN: 0735-1097
Popis: Background: Dofetilide is used to treat patients with atrial fibrillation, with recommended dosing based on the Cockcroft-Gault formula using actual body weight (ABW). Dose reduction or discontinuation may be necessary for excessive QT prolongation. We investigated whether initial dosing based on
Databáze: OpenAIRE