2G-2 Tissue-Type Imaging (TTI) of Prostate Cancer Based on Ultrasonic and Magnetic-Resonance Methods: Latest Developments
Autor: | D. Dail, S. Ramachandran, Jeffrey A. Ketterling, Christopher R. Porter, M. Lacrampe, Shreedevi Dasgupta, Ernest J. Feleppa |
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Rok vydání: | 2006 |
Předmět: |
medicine.medical_specialty
medicine.diagnostic_test Computer science medicine.medical_treatment Cancer Magnetic resonance imaging medicine.disease Imaging modalities Ultrasonic imaging Radiation therapy Prostate cancer medicine.anatomical_structure Prostate Biopsy medicine Ultrasonic sensor Radiology |
Zdroj: | 2006 IEEE Ultrasonics Symposium. |
DOI: | 10.1109/ultsym.2006.172 |
Popis: | Our prostate tissue-typing studies seek to develop imaging methods that have high sensitivity and specificity for visualizing cancerous regions of the prostate to improve the effectiveness of biopsy guidance, therapy targeting, and treatment monitoring. Spectral parameters obtained from radio-frequency (RF) ultrasonic (US) echo signals acquired from biopsy regions, along with the PSA are used to train a neural-network classifier. This method produced an ROC curve area of 0.84 compared to 0.64 obtained from B-mode, image-based classification. We are investigating the integration of ultrasonic and magnetic resonance (MR) methods to further improve our prostate tissue-typing methods. To take advantage of the independent information provided by US and MR, data acquired from the two imaging modalities need to be co-registered spatially. Therefore, we are developing effective means of 3D spatial co-registration of US and MR data along with histological data used for validation |
Databáze: | OpenAIRE |
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