Low-Dose Radiation Therapy for Benign Painful Skeletal Disorders: The Typical Treatment for the Elderly Patient?
| Autor: | Irenaeus A. Adamietz, Khashayar Fakhrian, Ralph Muecke, Guenter Kundt, M. Heinrich Seegenschmiedt, Oliver Micke, U. Schaefer |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Cancer Research
medicine.medical_specialty Radiation Bursitis Visual analogue scale business.industry Degenerative Disorder medicine.medical_treatment Pain scale medicine.disease 030218 nuclear medicine & medical imaging Surgery Radiation therapy 03 medical and health sciences 0302 clinical medicine Oncology 030220 oncology & carcinogenesis Low Dose Radiation Therapy medicine Radiology Nuclear Medicine and imaging Femur Prospective cohort study business |
| Zdroj: | International Journal of Radiation Oncology*Biology*Physics. 98:958-963 |
| ISSN: | 0360-3016 |
| DOI: | 10.1016/j.ijrobp.2016.12.012 |
| Popis: | Purpose To prospectively evaluate the short-term and long-term efficacy of low-dose radiation therapy (RT) for calcaneodynia, achillodynia, painful gonarthrosis, and painful bursitis trochanterica in elderly patients aged ≥70 years. Methods and Materials Between October 2011 and October 2013, patients aged ≥70 years with painful degenerative disorders of joints were recruited for a prospective trial. Single doses of 0.5 to 1.0 Gy and a total dose of 6.0 Gy per series were used. Pain was measured before and right after RT (early response) with a 10-point visual analogue scale. Additionally, pain relief was measured with the 4-point pain scale according to “von Pannewitz” immediately on completion of RT and during follow-up. We defined a good response as complete pain relief and markedly improved. Results A total of 166 evaluable patients with a mean age of 76.6 years (range, 70-90 years) with calcaneodynia (n=51), achillodynia (n=8), painful gonarthrosis (n=80), and painful bursitis trochanterica (n=27) were recruited. The mean visual analogue scale value before treatment was 6.38 and immediately upon completion of RT was 4.49 ( P P =.001). Conclusions Low-dose RT is a very effective treatment for the management of painful degenerative disorders of joints in the elderly. Low-dose RT offers a low-risk, genuinely conservative, noninvasive therapeutic alternative for elderly patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|