The Efficacy of Tocilizumab for Takayasu Arteritis: Review of the Literatures

Autor:	Ziyaeddin Aktop, Nesibe Karahan Yeşil, Metin Isik, Hatice Şahin, Ali Erdem Baki, İsmail Doğan
Rok vydání:	2015
Předmět:	medicine.medical_specialty Low toxicity medicine.drug_class business.industry Takayasu arteritis Disease Insidious onset Dermatology Surgery chemistry.chemical_compound Tocilizumab chemistry Giant cell Large vessel vasculitis medicine Corticosteroid skin and connective tissue diseases business
Zdroj:	Open Journal of Rheumatology and Autoimmune Diseases. :118-125
ISSN:	2164-005X 2163-9914
Popis:	Takayasu arteritis is a large vessel vasculitis of the young women with giant cells and granuloma formation. The diagnosis and management of the disease are really not so easy because of the insidious onset and the difficulties in assessment of disease activity. Nearly 60% of the patients are corticosteroid resistant or dependent and relapses are very frequent during taper of the dose [1]. The novel biologic agents as Anti-TNF, Rutiximab and Tocilizumab provide acceptable response rates with low toxicity. Herein, we reviewed the efficacy of Tocilizumab in Takayasu arteritis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9e26370e823f9a65b701753cd0084ad3 https://doi.org/10.4236/ojra.2015.54019 Zobrazit plný text záznamu