High-performance liquid chromatography of benzodiazepines using sorbents with thermally immobilized Carbowax 20M

Autor:	Roman Lodkowski, Andrzej L. Dawidowicz, Irena M. Choma
Rok vydání:	1992
Předmět:	chemistry.chemical_compound Chromatography Chemistry Silica gel Phase (matter) Organic Chemistry High selectivity Diol General Medicine Biochemistry High-performance liquid chromatography Analytical Chemistry
Zdroj:	Journal of Chromatography A. 600:109-113
ISSN:	0021-9673
DOI:	10.1016/0021-9673(92)85444-x
Popis:	The use of siliceous supports (controlled-porosity glass or silica gel) with thermally immobilized Carbowax 20M as sorbents for the separation of benzodiazepines by high-performance liquid chromatography (HPLC) was studied. The physico-chemical and chromatographic properties of these sorbents were compared with those of LiChrosorb DIOL and LiChrosorb RP-18. The results indicate that normal-phase HPLC chromatography of benzodiazepines using sorbents with thermally immobilized Carbowax 20M is a simple and effective method characterized by a simple binary mobile phase, very short column equilibration, high selectivity and a short time of analysis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9e07c17bee77cbcfc96fc613d4c87472 https://doi.org/10.1016/0021-9673(92)85444-x Zobrazit plný text záznamu