The Type of Storage of Autologous Blood Does Not Influence Homologous Transfusion Requirements in Hip Arthroplasty
| Autor: | A. Lorentz, C.-E. Dempfle, M. Klever, W. Segiet |
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| Rok vydání: | 2001 |
| Předmět: | |
| Zdroj: | Transfusion Medicine and Hemotherapy. 28:336-342 |
| ISSN: | 1660-3818 1660-3796 |
| DOI: | 10.1159/000050259 |
| Popis: | Background: The new German regulations for hemotherapy require the use of autologous blood as buffy coat-poor packed red cells (PRC) and fresh frozen plasma (FFP) or as leukocytedepleted whole blood (ldWB). There are no data, however, documenting reduced allogeneic transfusion rates and/or a better outcome with PRC/FFP or ldWB. We investigated whether storage as processed blood results in a different rate of homologous transfusion in patients undergoing surgery for hip arthroplasty. Patients and Methods: After informed consent 94 patients (48 men, 46 women, age 36–78 years) scheduled for hip arthroplasty and predepositing autologous blood were allocated at random to either of three groups: group WB (predeposit stored as unprocessed whole blood, surgery in the 5th week after the first donation), group ldWB (leukocyte-depleted whole blood, surgery in week 6) and group PRC/FFP (packed red cells and fresh frozen plasma, surgery in week 7). Three units were requested, deferral hemoglobin concentration was 11 g/dl. Results: Hemoglobin concentration prior to donation was measured as 13.8 ± 1.0, 14.2 plusmn; 1.1, 14.0 plusmn; 1.1 g/dl in groups WB, ldWB and PRC/FFP, respectively (mean plusmn; standard deviation); hemoglobin concentration prior to surgery as 13.0 plusmn; 1.3*, 13.5 plusmn; 1.4, 13.8 plusmn; 1.1* g/dl (*p Conclusions: The type of storage of autologous predeposit does not seem to influence the allogeneic transfusion rate in hip arthroplasty. The patients in groups ldWB and PRC/FFP were allowed more time for erythropoiesis, but red cells were lost due to processing of the blood. The data do not support the concept to leukocyte-deplete autologous blood or to produce components. |
| Databáze: | OpenAIRE |
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