| Popis: |
EGCG, the most abundant catechins of green tea exhibits several beneficial impacts on human health and helps in the amelioration of various pathological conditions including cardiovascular diseases, obesity, and cancer. The anti-obesity potential of EGCG depends on its potent antioxidant property, lipid metabolism modulatory action, and adipogenesis inhibitory ability. Moreover, EGCG also exhibits promising anticancer activity against cancer of different origins by inhibiting various features of tumorigenesis such as proliferation, evasion of apoptosis, angiogenesis, invasion and migration, and multidrug resistance through altering various signaling pathways. Taken as a whole, in this book chapter, we have discussed the detailed known mechanisms of anti-obesity and anticancer activities of EGCG and have also provided information about several novel targets of EGCG. |
