Methods, Measurements, and Interpretation of Animal Lung Function in Health and Disease

Autor: Daniel L. Costa, Jeffrey S. Tepper
Rok vydání: 2015
Předmět:
DOI: 10.1016/b978-0-12-404577-4.00017-5
Popis: This chapter examines the practical application of lung function tests that are or can be used in laboratory animals that provide analogues of clinical pulmonary function tests conducted on humans. Attention is given to the theory behind how changes in lung volume and flow occur and the techniques used to measure these changes in animals. With that knowledge, the various lung function tests and their usefulness in describing normal and abnormal lung function are discussed. The interpretation of functional changes detected in animals after experimental intervention remains predicated on our knowledge and experience in human pulmonary medicine yet also serves to illuminate and refine our understanding of normal and altered lung function in all mammals, including humans.
Databáze: OpenAIRE