Study of hematological profile in patients with chronic kidney disease
| Autor: | Gautam Panduranga, Ugendhar Perla |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test Transferrin saturation business.industry Incidence (epidemiology) Iron deficiency Disease medicine.disease Gastroenterology Bleeding diathesis Bleeding time hemic and lymphatic diseases Internal medicine medicine Population study business Kidney disease |
| Zdroj: | International Journal of Advances in Medicine. 7:11 |
| ISSN: | 2349-3933 2349-3925 |
| DOI: | 10.18203/2349-3933.ijam20195611 |
| Popis: | Background: Chronic Kidney Disease (CKD) with its high prevalence, morbidity and mortality, has become an important public health problem. The incidence and prevalence of CKD is increasing worldwide, including India. CKD is associated with a variety of hematological abnormalities, include anaemia, infections and bleeding diathesis. Anaemia is the most consistent hematological abnormality and is associated with poor quality of life and poor cardiovascular outcomes.Methods: A hospital based cross-sectional observational study was done to detect the prevalence of haematological abnormalities, correlation of anaemia with CKD stage and evaluation of iron deficiency. Newly diagnosed CKD (stages 3 to 5) patients were included in this study. Presence of anaemia (Hb%, haematocrit, MCV, peripheral smear), iron deficiency (TSAT, serum ferritin), thrombocytopenia, leucocyte count and coagulation abnormalities (PT, APTT) in different stages of CKD were studied.Results: All the subjects in study group had anaemia which was normocytic and normochromic and of moderate degree in most patients. The severity of anaemia progressed with stage of the disease. Iron deficiency was significantly prevalent (52% in the study population, with transferrin saturation (TSAT) |
| Databáze: | OpenAIRE |
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