A SNP-STR locus within the HLA class II region: Sequence and population data of D6S2822

Autor: B. Glock, Wolfgang R. Mayr, R.B.K. Reisacher, E.M. Dauber, S. Wenda, G. Dorner
Rok vydání: 2006
Předmět:
Zdroj: International Congress Series. 1288:334-336
ISSN: 0531-5131
DOI: 10.1016/j.ics.2005.09.003
Popis: Population genetics and sequence structure of the tetranucleotide short tandem repeat locus D6S2822 were investigated in an Austrian Causasoid population sample in order to reveal information about its usefulness for HLA haplotyping, linkage analyses and forensic testing. Seven different sized alleles additionally showing sequence polymorphism could be detected. As for allele distribution and statistic parameters D6S2822 turned out to be a moderately repetitive and informative marker. Due to the A/G SNP adjacent to the repeat region this locus might also be of interest for phylogenetic studies.
Databáze: OpenAIRE