Metabolic indicators in diagnostics and prediction of course of subclinical and clinical mastitis in goats after parturition

Autor: K. V. Plemyashov, A. V. Filatova, D. N. Sandakzi, V. S. Avdeenko
Rok vydání: 2023
Zdroj: Legal regulation in veterinary medicine. :72-77
ISSN: 2782-6252
DOI: 10.52419/issn2782-6252.2022.4.72
Popis: The symptom complex of the inflammatory process in the udder was established in the process of clinical examination in 27.69±1.79 percentage of goats at the beginning of lactation. In the early postpartum period, in sick goats with catarrhal or serous mastitis, a decrease in buffer bases, glucose concentration, and the VH/AcAc coefficient were found. The content of total protein is reduced by 1.22 times, and the level of albumin is reduced by 1.51 times. The indices of AST and ALT, CHF, with catarrhal mastitis are reduced, and the indices of LDH are increased relative to other groups of animals studied, which indicates that the destabilization of metabolite metabolism during the functioning of the liver is included in the pathological process. The level of ceruloplasmin ranged from 7.97 to 141.6 mg / dl, in the blood of goats with clinical mastitis, while with subclinical mastitis from 6.74 to 89.14 mg / dl, and in the control group (clinically healthy) was in range from 9.32 to 46.137 mg/dL. Significant differences were obtained in a positive test for the level of ceruloplasmin and Creactive protein in goats with mastitis. In goats with subclinical mastitis, the level of the studied hormones was within the confidence interval, which allows us to consider hormonal imbalance as a proven cause of subclinical, catarrhal, serous mastitis and the likelihood of hormone dependence of udder inflammation in goats shortly after birth. In animals with subclinical mastitis and with clinical signs of catarrhal or serous mastitis, an increase in the level of diene conjugates by 1.87 times, and the concentration of intermediate products of ketodienes and conjugated triune’s by 1.75 times. By 38.0% of the concentration of stable metabolites of nitric oxide and a decrease of 13.1% in the content of vitamin E. In the blood of progesterone and estradiol, as well as the LPO-AOD systems, have a sufficiently high diagnostic value, allowing monitoring the course of the pathological process in the udder of goats and monitoring the treatment protocol.
Databáze: OpenAIRE