A short and efficient asymmetric synthesis of komaroviquinone

Autor:	Yutaka Suto, Genji Iwasaki, Noriyuki Yamagiwa, Kento Kaneko
Rok vydání:	2010
Předmět:	Natural product biology Chemistry Dracocephalum Organic Chemistry Enantioselective synthesis Total synthesis biology.organism_classification Biochemistry Combinatorial chemistry chemistry.chemical_compound Drug Discovery Organic chemistry Komaroviquinone
Zdroj:	Tetrahedron Letters. 51:6329-6330
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2010.09.110
Popis:	An asymmetric total synthesis of komaroviquinone ( 1 ), which is a natural product isolated from Dracocephalum komarovi and shows novel potent trypanocidal activity, was achieved in five steps from the known starting materials. The synthetic route is shorter and more efficient than the reported methods and also useful for the scale-up synthesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9d8aacdbead689db80029832d28e6949 https://doi.org/10.1016/j.tetlet.2010.09.110 Zobrazit plný text záznamu Full Text from ScienceDirect