Synthesis of steroid hormones highly labeled with tritium and their use for assessing the activity of aromatase
| Autor: | I. Yu. Nagaev, I. V. Kondakova, V. P. Shevchenko, L. A. Kolomiets, N. V. Bochkareva, N. F. Myasoedov, K. V. Shevchenko |
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| Rok vydání: | 2004 |
| Předmět: |
medicine.medical_specialty
biology urogenital system Chemistry medicine.medical_treatment Cancer Myoma medicine.disease Endometrium female genital diseases and pregnancy complications Steroid Endocrinology medicine.anatomical_structure Internal medicine medicine biology.protein Tritium Androstenedione Physical and Theoretical Chemistry Aromatase reproductive and urinary physiology Hormone |
| Zdroj: | Radiochemistry. 46:494-499 |
| ISSN: | 1608-3288 1066-3622 |
| DOI: | 10.1007/s11137-005-0018-5 |
| Popis: | Steroids highly labeled with tritium (progesterone, estradiol, androstenedione) were synthesized and used to assess the activity of aromatase at various pathologies. The high activity of aromatase in endometrium in endometrium cancer patients without myoma corresponds to a worse prognosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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