Synthesis and characterization of some new heterocyclic compounds from α, β- unsaturated carbonyl system

Autor: null Muna A. Othman Salem, null Hana A. A. Mageed, null Huda S. Muftah, null Reda F. El- Ezabi, null Fayrouz A. Khaled
Rok vydání: 2021
Zdroj: Open Journal of Pharmaceutical Science and Research. :56-63
DOI: 10.36811/ojpsr.2021.110015
Popis: An efficient and facile one pot synthesis of 3,4-dihydropyrimidinones (Belinelli compound) from furfural, acetylacetone and urea under solvent free conditions was performed, resulted in promising yield. These compounds reacted with benzaldehyde and furfural to give the corresponding chalcones. Chalcones are used to synthesize several derivatives like pyrazolines isoxazoles and pyrimidines having different heterocyclic ring systems. Keywords: Belinelli compounds; Chalcone; Pyrazolines isoxazoles; Pyrimidines
Databáze: OpenAIRE