Early-Life Stress as a Probe to Study the Opioid System in Developing Rodents
| Autor: | Alberto Loizzo, Stefano Loizzo |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
business.industry
Early life stress 030209 endocrinology & metabolism Disease Opioid system Overweight Bioinformatics Pathophysiology 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Intensive care Medicine medicine.symptom business Opioid peptide 030217 neurology & neurosurgery Hypothalamic–pituitary–adrenal axis |
| Zdroj: | Methods in Molecular Biology ISBN: 9781071608838 |
| Popis: | The developmental origins of disease or fetal programming model predict that early (intrauterine and/or postnatal) exposures to external insults of sufficient length and intensity may have enduring or lifelong consequences for physical and psychological health. The method described in this chapter considers an animal model to study the pathophysiological alterations connected to an HPA axis (hypothalamic-pituitary-adrenal) hyperactivity that are induced by an early-life stressful procedure involving the opioid system. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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