Herpes simplex virus encephalitis following corticosteroids and cranial irradiation
| Autor: | D. H. Jacobs, K. L. Tyler |
|---|---|
| Rok vydání: | 1999 |
| Předmět: | |
| Zdroj: | Neurology. 52:1106-1106 |
| ISSN: | 1526-632X 0028-3878 |
| DOI: | 10.1212/wnl.52.5.1106-c |
| Popis: | To the Editor: We thank Fodor et al. for expanding our appreciation of the clinical spectrum of herpes simplex virus encephalitis (HSVE).1 Fodor et al. noted that patients with HSVE can present with mild or atypical symptoms, without the characteristic pleocytosis in the CSF, and that HSVE can be precipitated by the administration of corticosteroids. Other authors have also suggested that HSVE should be considered an opportunistic infection in cases in which patients are immunocompromised.2,3 The increasing appreciation of this fact has been enabled in part by the ease of diagnosing HSVE from CSF with the introduction of new PCR techniques. We present a 42-year-old woman with intracranial metastases of breast cancer treated for 1 month with steroids and cranial irradiation. The patient is a right-handed woman who presented with facial numbness and falling to the right 4 years after completing initial treatment for breast cancer. She had been treated with lumpectomy, chemotherapy, and local radiation 4 years previously and, until shortly before presentation, had no signs of persisting or recurrent disease. Her mental status was normal. She had numbness in V1, V2, and V3 on the right and … |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|