Evaluation of a High Concentrated Contrast Media Injection Protocol in Combination with Low Tube Current for Dose Reduction in Coronary Computed Tomography Angiography
| Autor: | Xiu Jin, Dingbiao Mao, Cheng Li, Kailei Shi, Yanqing Hua, Ming-peng Wang, Jianrong Xu, Yibo Sun |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
business.industry media_common.quotation_subject Center (group theory) 030204 cardiovascular system & hematology 030218 nuclear medicine & medical imaging Coronary arteries 03 medical and health sciences Contrast medium 0302 clinical medicine medicine.anatomical_structure Hounsfield scale medicine Image noise Contrast (vision) Radiology Nuclear Medicine and imaging Radiology business Nuclear medicine Prospective cohort study Body mass index media_common |
| Zdroj: | Academic Radiology. 24:1482-1490 |
| ISSN: | 1076-6332 |
| DOI: | 10.1016/j.acra.2017.07.001 |
| Popis: | Rationale and Objectives The study aimed to prospectively evaluate the radiation dose reduction potential and image quality (IQ) of a high-concentration contrast media (HCCM) injection protocol in combination with a low tube current (mAs) in coronary computed tomography angiography. Materials and Methods Eighty-one consecutive patients (mean age: 62 years; 34 females; body mass index: 18–31) were included and randomized-assigned into two groups. All computed tomography (CT) examinations were performed in two groups with the same tube voltage (100 kV), flow rate of contrast medium (5.0 mL/s), and iodine dose (22.8 g). An automatic mAs and low concentration contrast medium (300 mgI/mL) were used in group A, whereas effective mAs was reduced by a factor 0.6 along with HCCM (400 mgI/mL) in group B. Radiation dose was assessed (CT dose index [CTDIvol] and dose length product), and vessel-based objective IQ for various regions of interest (enhancement, noise, signal-to-noise ratio, and contrast-to-noise ratio), subjective IQ, noise, and motion artifacts were analyzed overall and vessel-based with a 5-point Likert scale. Results The CT attenuation of coronary arteries and image noise in group B were significantly higher than those in group A (ranges: 507.5–548.1 Hounsfield units vs 407.5–444.5 Hounsfield units; and 20.3 ± 8.6 vs 17.7 ± 8.0) (P ≤ 0.0166). There was no significant difference between the two groups in signal-to-noise ratio, contrast-to-noise ratio, and subjective IQ of coronary arteries (29.4–31.7, 30.0–37.0, and medium score of 5 in group A vs 29.4–32.4, 27.7–36.3, and medium score of 5 in group B, respectively, P ≥ 0.1859). Both mean CTDIvol and dose length product in group B were 58% of those of group A. Conclusions HCCM combined with low tube current allows dose reduction in coronary computed tomography angiography and does not compromise IQ. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|