Change of Biomechanical Parameters in the Lower Jaws of Rabbits with Experimental Osteoporosis after Implantation of Calcium-Phosphate Bioceramic Material in the Greater Trochanter Region
Autor: | Girts Salms, Vladimirs Kasyanovs, Vita Zalite, Vladislavs Ananjevs, Sandris Petronis, Liga Stipniece, Janis Vetra, Ilze Šalma, Andrejs Skagers |
---|---|
Rok vydání: | 2016 |
Předmět: |
Greater trochanter
Materials science Mechanical Engineering Osteoporosis chemistry.chemical_element Strain (injury) Bioceramic Calcium medicine.disease Bone tissue medicine.anatomical_structure stomatognathic system chemistry Strontium ranelate Mechanics of Materials medicine General Materials Science Biomedical engineering medicine.drug |
Zdroj: | Key Engineering Materials. 721:224-228 |
ISSN: | 1662-9795 |
DOI: | 10.4028/www.scientific.net/kem.721.224 |
Popis: | Investigation of biomechanical properties of the rabbit bone tissue from a corner of the lower jaw was done. Experimental osteoporosis was induced by ovariectomy and following injections of methylprednisolone. The defects in the greater trochanter region was created and filled with granules of a hydroxyapatite and tricalcium phosphate (HAP/TCP 30/70) or HAP/TCP 30/70 together with 5% strontium ranelate. After 3 month animals were euthanased, squared samples have been cut out from a corner of the lower jaw and tested on a bend. Results of research show, that the corner of a lower jaw in rabbit becomes more rigid after filling of defects in the greater trochanter region with granules of a hydroxyapatite and tricalcium phosphate (HAP/TCP 30/70) or granules together with strontium ranelate. The ultimate strain for the bone tissue in the 2nd and 3rd group is less, than for control group. Thus, local uses calcium – phosphatic bioceramic material around the greater trochanter region improves biomechanical parameters of a bone tissue in the lower jaw of animals. |
Databáze: | OpenAIRE |
Externí odkaz: |