ChemInform Abstract: A New Synthetic Access to N-Alkylated Nitrones Through Lewis Acid Catalyzed Conjugate Additions of Aldoximes

Autor:	Sumito Seki, Kimitaka Nakama, Shuji Kanemasa
Rok vydání:	2010
Předmět:	inorganic chemicals chemistry.chemical_classification Iodide chemistry.chemical_element General Medicine Zinc Alkylation Catalysis chemistry.chemical_compound chemistry Organic chemistry Lewis acids and bases Boron trifluoride Conjugate
Zdroj:	ChemInform. 32
ISSN:	1522-2667 0931-7597
Popis:	In the presence of Lewis acid catalysts, aldoximes react with α,β-unsaturated carbonyl compounds at room temperature to give N-alkylnitrones in good yields. Combination of two Lewis acid catalysts, zinc(II) iodide/boron trifluoride etherate (50 mol%/50 mol%), is the best choice to mediate the reactions producing N-alkylated nitrones in excellent yields. In this procedure, a variety of aldoximes and α,β-unsaturated carbonyl acceptors can be employed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9d1c6fb0a56b85c2792357b1fd4df6a4 https://doi.org/10.1002/chin.200150061 Zobrazit plný text záznamu Plný text