| Popis: |
To effect enzyme-catalyzed reactions of small molecules, nature has evolved coenzymes. During the first 60 years of this century, most of the coenzymes of metabolism (diphosphothiamin, ATP, biotin, coenzyme A, pyridoxal phosphate, folic acid, FMN-FAD, NAD-NADP, lipoic acid, cobamides, and quinones) were defined. Most of these coenzymes were found to be cosmopolitan. Their distribution among prokaryotes and eukaryotes strongly supported the doctrine of comparative biochemistry, i.e., what was true for bacteria also was true for plants and animals, there being only one major exception: cobamides apparently played no role in the evolution of plants. |
