The absence of both kidneys associated with hereditary abnormalities in mice

Autor: Halsey Joseph Bagg
Rok vydání: 1924
Předmět:
Zdroj: Experimental Biology and Medicine. 21:228-229
ISSN: 1535-3699
1535-3702
DOI: 10.3181/00379727-21-116
Popis: Recently the writer recorded the occurrence of fifty mice having in each case a solitary kidney.1 They constituted 16 2/3 per cent of a group of 300 autopsied animals, descendants of animals that were subjected to light doses of x-ray irradiation. The treatment was apparently associated with the production of hereditary abnormalities of the eyes, feet and other parts of the body.Several matings have now been made where in each case both parents had but one kidney, and the number of young per litter was considerably less than the average for animals with normal kidneys. Several of the young animals died during the first week of life and were promptly destroyed by their mother. The examination of a single litter of seven mice apparently throws considerable light on the high mortality shown in such animals and is considered of sufficient interest to warrant a brief report. In this instance, however, the male parent had but one kidney and was blind in the right eye, while the mother, although apparently norma...
Databáze: OpenAIRE