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Background: Patients with end stage kidney disease (ESKD) face higher risk of life-threatening event including cardiovascular disease. Various risk factors have identified as an agent influencing their life prognosis. The study's purpose was to evaluate the risk factors related to the outcomes of Japanese patients with dialysis induction. In this brief report, we present this cohort study protocol and the baseline characteristics. Methods: Ibaraki Dialysis Initiation Cohort Study, iDIC Study, is a prospective multi-center cohort study in collaboration with 60 facilities in Ibaraki prefecture, Japan. We collected baseline data from clinical records, blood and urine samples in diabetic nephropathy, hypertensive nephrosclerosis and chronic glomerulonephritis Results: Sixty tertiary care institutions participated in the iDIC study, and 636 entries were analyzed. In this brief report, we present the baseline data of the entries in a comparison with the data of other similar cohort studies. Of the 636 patients, 424 were males and 212 were females. The average age was 67.4±13.1 years old. As the primary kidney disease, 327 cases (51.4%) were diagnosed as diabetic nephropathy, 101 cases (15.9%) as hypertensive nephrosclerosis, and 114 cases (17.9%) as chronic glomerulonephritis. The average serum creatinine value was 9.1 ± 2.9 mg/dL, and the average estimated glomerular filtration rate (eGFR) was 5.6 ± 1.8 mL/min/1.73m2. Conclusion: We presented the study protocols and baseline characteristics of iDIC Study. Regarding as clinical characteristics of newly induced dialysis patients, the same trend was observed in the other cohort studies. Another study is underway to explore prognostic factors based on the iDIC Study's findings. |
