Phenolic composition, antioxidant, antibacterial and anti-inflammatory activities of leaf and stem extracts from Cryptotaenia japonica Hassk
| Autor: | Zheng Ying, Liu Ting, Jiahao Chen, Feijun Luo, Lu Jun, Xinjing Fu |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
030109 nutrition & dietetics Antioxidant ABTS Traditional medicine Chemistry medicine.drug_class DPPH medicine.medical_treatment 04 agricultural and veterinary sciences Phenolic acid Cryptotaenia japonica 040401 food science Anti-inflammatory 03 medical and health sciences chemistry.chemical_compound 0404 agricultural biotechnology Apigenin medicine Antibacterial activity Agronomy and Crop Science |
| Zdroj: | Industrial Crops and Products. 122:522-532 |
| ISSN: | 0926-6690 |
| DOI: | 10.1016/j.indcrop.2018.06.026 |
| Popis: | Cryptotaenia japonica Hassk. is a traditional medicinal plant in China to treat different diseases, as well as an edible leafy vegetable, but its biological functions is unknown. This study aimed to evaluate the antioxidant, antibacterial and anti-inflammatory activities of different phenolic extracts/fractions, which prepared with four kinds of methods and three kinds of polar solvent from Cryptotaenia japonica Hassk. leaf and stem. DPPH, ABTS, and reducing power assays were used to evaluate their antioxidant activity; antibacterial activity assay was assessed by Escherichia coli, Staphylococcus aureus, Bacillus subtilis, and β-hemolytic streptococcus; inflammatory cytokine secretions were detected by ELISA assay. UPLC-ESI-MS/MS was used to identify the phenolics compounds. Compared with other extracts/fractions, the ethyl acetate fraction (EAF) had the highest amount of total phenolic and total flavonoids. It also exhibited strong DPPH, ABTS radical scavenging activities, reducing power, and antibacterial activity. This fraction also exhibited greater inhibitory effects on secretion of inflammatory cytokines. Six kinds of phenolic acid compounds from Cryptotaenia japonica Hassk. were indentified and luteolin (106806.1 μg/g dried weight, DW), apigenin (13780.8 μg/g DW) and p-coumaric acid (8004.8 μg/g DW) are main compounds. The results suggest that Cryptotaenia japonica Hassk. is a promising source of natural antioxidant, antibacterial and anti-inflammatory constituents for application in the food and pharmaceutical industries. |
| Databáze: | OpenAIRE |
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