Early infant feeding effect on growth and body composition during the first 6 years and neurodevelopment at age 72 months

Autor: Aline Andres, Patrick H. Casey, Ginger McCorkle, Jayne Bellando, D. Keith Williams, Seth T. Sorensen, Clark R. Sims, Sarah R. Sobik, Thomas M. Badger
Rok vydání: 2020
Předmět:
Zdroj: Pediatric Research. 90:140-147
ISSN: 1530-0447
0031-3998
Popis: This study longitudinally characterized the developmental status, growth, and body composition of children who were fed human milk (breastfed, BF), cow’s milk-based (MF), or soy protein-based (SF) infant formula from 3 to 12 months. Standardized anthropometrics and dual-energy X-ray absorptiometry were used to characterize growth and body composition at 3, 6, 9, 12, 24, 36, 48, 60, and 72 months (NCT00616395). Preschool Language Scale-3, Children’s Memory Scale Index (CMS), and Wechsler Preschool and Primary Scale of Intelligence were administered at age 72 months. Mixed-effects models adjusting for gestational age, birth weight, child race and sex, parental education, and maternal IQ were performed. Body Mass index (BMI) was significantly lower between 24 and 72 months in BF children compared to SF children. At 3 and 6 months, BF infants had significantly higher fat mass (FM) than SF infants, whereas BF children had significantly lower FM at 36 and 48 months than SF children. Delayed Recognition Index of the CMS was higher for SF than for MF participants (p = 0.009). There was no other significant difference in developmental outcomes between groups. In conclusion, BF, MF, and SF support adequate growth and development up to age 6 years.
Databáze: OpenAIRE
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