Correlates of response to anti-PD-1 immune checkpoint blockade (ICB) in mismatch repair proficient (MMRp) and deficient (MMRd) patients (pts) with metastatic castration resistant prostate cancer (mCRPC)

Autor: Niven Mehra, Antoine G. van der Heijden, Mark A.J. Gorris, Harm Westdorp, Jack A. Schalken, Marjolijn J. L. Ligtenberg, Katrien Grünberg, Tjitske Duiveman-de Boer, Jennifer Jones, Jolanda De Vries, Kiek Verrijp, James L. Gulley, Inge M. van Oort, Alfred Witjes, Winald R. Gerritsen, Thomas J. Van Ee, Minke Smits, Astrid Eijkelenboom, Michiel Sedelaar, Johannes Textor
Rok vydání: 2018
Předmět:
Zdroj: Journal of Clinical Oncology. 36:5036-5036
ISSN: 1527-7755
0732-183X
Popis: 5036Background: Predictive biomarkers are needed to improve the proportion of pts with mCRPC that may benefit from anti-PD-1/PD-L1 ICB. A comprehensive characterization of both genomic alterations ...
Databáze: OpenAIRE