Is there any significance for intracellular crystals in plasma cells from patients with monoclonal gammopathies?

Autor:	Franck Geneviève, J. Gardais, Marc Zandecki, C. Foussard, V. Delisle
Rok vydání:	2001
Předmět:	Pathology medicine.medical_specialty biology Renal function Hematology General Medicine medicine.disease hemic and lymphatic diseases Immunopathology Cytology Monoclonal biology.protein medicine Antibody Adult Fanconi syndrome Multiple myeloma Intracellular
Zdroj:	European Journal of Haematology. 67:119-122
ISSN:	0902-4441
Popis:	Several plasma cells morphological changes have been described in monoclonal gammopathies, including intracytoplasmic crystals. We report one case of indolent kappa-chain multiple myeloma with renal insufficiency, featuring plasma cells with Auer-rod-like intracytoplasmic inclusions. The relationship between such aberrations and those found in multiple-myeloma-associated adult Fanconi syndrome is discussed. The significance of intracellular storage and crystallisation of immunoglobulin within plasma cells remains partially unknown.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9c8b9afb3d90e5c7e5513f1764c4a7f8 https://doi.org/10.1034/j.1600-0609.2001.t01-1-00485.x Zobrazit plný text záznamu Plný text ve formátu PDF