(Neuro-)Endokrine Tumoren des Magens sind auf dem Vormarsch: Gute Prognose bei frühem Nachweis
| Autor: | J. Steinberg, Günter Klöppel, Faiss S, T. Weinke, T. Zimmer, C. Schwertner, Hans Scherübl, Ulrich Stölzel, Liehr Rm, H.-U. Jahn |
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| Rok vydání: | 2009 |
| Předmět: |
Endoscopic ultrasound
medicine.medical_specialty medicine.diagnostic_test business.industry Stomach Early detection General Medicine Neuroendocrine tumors medicine.disease Asymptomatic Optimal management Surgery medicine.anatomical_structure medicine Radiology Good prognosis Gastritis medicine.symptom business |
| Zdroj: | DMW - Deutsche Medizinische Wochenschrift. 134:1529-1535 |
| ISSN: | 1439-4413 0012-0472 |
| DOI: | 10.1055/s-0029-1233975 |
| Popis: | Neuroendocrine tumors (NET) of the stomach are on the rise. In the United States they have increased about tenfold in the last 35 years. Prognosis has been much improved over the last three to four decades. Nowadays most of such NETs are diagnosed at an early stage. Quite often gastric NETs are found incidentally during a gastroscopy, performed for other reasons. Most of the asymptomatic, well differentiated gastric NETs are less than 2 cm in diameter. Conservative management and endoscopic surveillance is adequate for well differentiated, multifocal type 1 or type 2 gastric NETs (gastric carcinoids) of 10-20 mm , unless they are angio-invasive, have infiltrated into the muscularis propria or have metastasized. Endoscopic ultrasound is the method of choice to determine tumor size and depth of infiltration. Surgery is, however, indicated for all NETs larger than 20 mm. For optimal management tumor biology, type and stage of the neoplasm as well as the individual situation of the patient have to be taken into account. Most of the patients can be treated conservatively and be followed up with endoscopic surveillance. |
| Databáze: | OpenAIRE |
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