New Acetylated Saponins from the Leaves of Trevesia palmata

Autor:	Do Quyen, Bui Huu Tai, Phan Van Kiem, Duong Binh Vu, Le Thi Thanh Thao
Rok vydání:	2018
Předmět:	0106 biological sciences Pharmacology 010405 organic chemistry Chemistry Plant Science General Medicine Trevesia palmata 01 natural sciences 0104 chemical sciences Complementary and alternative medicine Acetylation Drug Discovery Botany 010606 plant biology & botany
Zdroj:	Natural Product Communications. 13:1934578X1801300
ISSN:	1555-9475 1934-578X
DOI:	10.1177/1934578x1801300407
Popis:	Two new acetylated saponins, acetyltrevesiasaponins A (1) and B (2), were isolated from the leaves of Trevesia palmata. Their chemical structures were determined by analysis of HR-ESI-MS and NMR spectra. Compound 2 was also confirmed by alkaline hydrolysis and identification its prosapogenin 2a. Compounds 1, 2, and 2a were evaluated inhibitory effect on NO production in LPS stimulated BV2 cells. Compound 2 showed weak activity (IC50 40.7 μM).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9c78631db3c055795acb60299a33be17 https://doi.org/10.1177/1934578x1801300407 Zobrazit plný text záznamu