Evaluation of synthetic antidiuretic hormone as a corrective substance following a head-down tilt

Autor:	L. Kh. Pastushkova, V. B. Noskov, G. Yu. Vasilieva, I. A. Nichiporuk, Irina M. Larina
Rok vydání:	2012
Předmět:	medicine.medical_specialty Physiology business.industry Renal function Head-Down Tilt Orthostatic vital signs Endocrinology Physiology (medical) Internal medicine medicine Vasopressin Analog business Desmopressin Homeostasis medicine.drug Hormone Antidiuretic
Zdroj:	Human Physiology. 38:781-785
ISSN:	1608-3164 0362-1197
Popis:	Effects of synthesized desmopressin, analog of antidiuretic hormone, and water-salt supplement on the renal function and orthostatic stability were studied in 6 normal male subjects after 12-hr. head-down tilt (12 degrees). The combination of water-salt homeostasis normalizing methods was effective in retaining excessive liquid and salts. Moreover, tolerance of the standard 20-min. passive standing test improved significantly. Hence, it was demonstrated that intake of synthetic vasopressin analog combined with WSS counteracted hypohydration of organism due to HDT and improved orthostatic tolerance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9c6bebb68d846f00218a6a67d7873e59 https://doi.org/10.1134/s0362119712070171 Zobrazit plný text záznamu Full text from SpringerLink