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Background and aims: To evaluate the foot plantar temperature in normal and diabetic patient (DM) and to assess development of diabetic foot ulceration could be predicted by the foot temperature measurement with infrared thermography (IR). Materials and methods: The first investigation was designed for assessment of correlation between foot plantar temperature and diabetic foot. Eighteen normal controls were compared to 23 DM without polyneuropathy (Group I), 20 DM with polyneuropathy (Group II), and 16 DM with polyneuropathy plus diabetic foot ulcer (Group III). Temperature were assessed using IR in six standard plantar sites; medial longitudinal arch (MLA), lateral longitudinal arch (LLA), heel, 5th toe, 3rd metatarsal head (3MTH), and greater toe (GT), and mean foot temperature; MFT. The second investigation would be followed after 5 years among the same subjects except for control group. Results: Sixteen Group I subjects were contacted but ten accepted the follow-up investigation. Thirteen of fifteen contacted Group II and eight of eleven contacted Group III subjects accepted to be enrolled in the 2nd investigation. In the 1st investigation, the duration of diabetes was significantly longer in Group II and Group III than in Group I (p |