Butyrylcholinesterase activity among farm male pesticide handlers in Naivasha, Kenya

Autor: E.N.M. Njagi, George O. Orinda, Lucy A. Mambo
Rok vydání: 2013
Předmět:
Zdroj: African Journal of Agricultural Research. 8:4474-4483
ISSN: 1991-637X
Popis: To investigate the incidence of pesticide poisoning using serum cholinesterase activity patterns in a horticultural farm, 616 people comprising of 496 pesticide handlers (test group) and a control group of 120 persons participated in the study. A semi-structured questionnaire was used to obtain demographic information, while the activities of serum cholinesterase, serum glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase, alkaline phosphatase and bilirubin were estimated using standard commercial kits and absorbance measured using kinetic colorimetric tests. All the pesticide handlers (100%) were males, with majority (80.3%) aged 20 to 35 years old. Of the test population, 6% had significant cholinesterase enzyme depressions with no symptoms of exposure recorded. Significant difference (p 0.05) between the test and control groups based on years of handling pesticides. Use of pesticides in successive spray seasons significantly inhibited cholinesterase activity among the spray team, supervisors and harvesters (p
Databáze: OpenAIRE