The M‐N‐V‐A‐B‐D blood group system of chimpanzee and other apes: Serology and genetics

Autor:	W. W. Socha, Jan Moor-Jankowski
Rok vydání:	1993
Předmět:	Genetics General Veterinary Antigen Genetic model Monoclonal biology.protein Animal Science and Zoology Biology Antibody Allele Immune sera Phenotype Serology
Zdroj:	Journal of Medical Primatology. 22:3-6
ISSN:	1600-0684 0047-2565
Popis:	Poly- and monoclonal anti-M and anti-N reagents detect on the red cells of anthropoid apes the M and/or N antigens which are similar to, but not identical with human M and N. A series of V-A-B-D specificities, closely related to the M-N system, are recognized on ape red blood cells by chimpanzee immune sera. To account for the distributions of the M-N--V-A-B-D types in man and in various apes, a genetic model is proposed that assumes the existence of two independent pairs of alleles: M/m, and N/n. In the processes of speciation, some of the alleles were lost or replaced by multiple mutations, resulting in chimpanzee in a series of codominant alleles responsible for as many as 16 M-N--V-A-B-D phenotypes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9c4cb5aeaeda04d824f4a68f8a119b62 https://doi.org/10.1111/j.1600-0684.1993.tb00629.x Zobrazit plný text záznamu