Adherence to nutrition-based cancer prevention guidelines and breast, prostate and colorectal cancer risk in the MCC-Spain case-control study
| Autor: | Gemma Castaño-Vinyals, Esther Gracia-Lavedan, Michelle A. Mendez, Javier Llorca, Guillermo Fernández-Tardón, Jose Andrés Lorca, Adonina Tardón, Silvia de Sanjose, Carmen Urtiaga, Amaia Molinuevo, Verónica Dávila-Batista, José Juan Jiménez-Moleón, Carmen Vidal, José María Huerta, Adela Castelló, Jesús Castilla, Jone M. Altzibar, Vicente Martín, Nuria Aragonés, Victor Moreno, Dora Romaguera, Cristóbal Llorens-Ivorra, Marcela Guevara, Rocío Olmedo-Requena, Rafael Marcos-Gragera, Trinidad Dierssen-Sotos, Pilar Amiano, Marina Pollán, Jordi de Batlle, Beatriz Pérez-Gómez, Manolis Kogevinas, Antonio J. Molina, Inés Gómez-Acebo |
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| Rok vydání: | 2017 |
| Předmět: |
Oncology
Cancer Research medicine.medical_specialty education.field_of_study Cancer prevention Colorectal cancer business.industry Population Case-control study Cancer medicine.disease Lower risk 03 medical and health sciences Prostate cancer 0302 clinical medicine Breast cancer 030220 oncology & carcinogenesis Internal medicine medicine 030212 general & internal medicine business education |
| Zdroj: | International Journal of Cancer. 141:83-93 |
| ISSN: | 0020-7136 |
| Popis: | Prostate, breast and colorectal cancer are the most common tumours in Spain. The aim of the present study was to evaluate the association between adherence to nutrition-based guidelines for cancer prevention and prostate, breast and colorectal cancer, in the MCC-Spain case-control study. A total of 1,718 colorectal, 1,343 breast and 864 prostate cancer cases and 3,431 population-based controls recruited between 2007 and 2012, were included in the present study. The World Cancer Research Fund/American Institute for Cancer Research (WCRC/AICR) score based on six recommendations for cancer prevention (on body fatness, physical activity, foods and drinks that promote weight gain, plant foods, animal foods and alcoholic drinks; score range 0-6) was constructed. We used unconditional logistic regression analysis adjusting for potential confounders. One-point increment in the WCRF/AICR score was associated with 25% (95% CI 19-30%) lower risk of colorectal, and 15% (95% CI 7-22%) lower risk of breast cancer; no association with prostate cancer was detected, except for cases with a Gleason score ≥7 (poorly differentiated/undifferentiated tumours) (OR 0.87, 95% CI 0.76-0.99). These results add to the wealth of evidence indicating that a great proportion of common cancer cases could be avoided by adopting healthy lifestyle habits. |
| Databáze: | OpenAIRE |
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