CICULATORY LEVELS OF RETINOL-BINDING PROTEIN 4 IN PATIENTS WITH TYPE 2 DIABETES, COMPLICATED BY NON-ALCOHOLIC FATTY LIVER DISEASE
| Autor: | A. K. Pochernyayev, M. Y. Gorshunska, E. Jаnsen, Zh. A. Leshchenko, T. V. Tyzhnenko, N. A. Kravchun, Yu. I. Karachentsev, A. I. Gladkih, N. V. Zavadska, Y. A. Opaleiko, V. V. Poltorak, A. A. Cherniaieva, N. S. Krasova, I. V. Chernyavskaya |
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| Rok vydání: | 2014 |
| Předmět: |
Retinol binding protein 4
medicine.medical_specialty biology business.industry Endocrinology Diabetes and Metabolism Fatty liver Type 2 Diabetes Mellitus Type 2 diabetes Disease medicine.disease Pathology and Forensic Medicine Endocrinology Insulin resistance Internal medicine Circulatory system biology.protein medicine In patient business |
| Zdroj: | Problems of Endocrine Pathology. 48:7-14 |
| ISSN: | 2518-1432 2227-4782 |
| DOI: | 10.21856/j-pep.2014.2.01 |
| Popis: | It was determined levels of retinol-binding protein 4 (RBP4) in the blood of patients with type 2 diabetes mellitus with non-alcoholic fatty liver disease or its absence. In patients with type 2 diabetes was verified a significant increase of circulating levels of RBP4, the severity of which was significantly higher in non-alcoholic fatty liver disease, as well as their direct correlation with the presence of complications. The data obtained justify the use of indicators of circulatory levels of RBP4 as a new marker of the risk of non-alcoholic fatty liver disease in patients with type 2 diabetes and the selection of anti-diabetic therapy. |
| Databáze: | OpenAIRE |
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