Use and Application of Cytokines and Growth Factors in Laboratory Diagnostic Procedures

Autor: S. Yamamoto, K. Ikebuchi, S. Sekiguchi, Mitsuhiro Fujihara, T. Nakase
Rok vydání: 1997
Předmět:
Zdroj: Cytokines and Growth Factors in Blood Transfusion ISBN: 9781461284352
DOI: 10.1007/978-1-4613-1137-9_5
Popis: Cytokines are potent regulating polypeptides or glycoproteins which mediate a variety of biological and physiological processes involved in cellular and humoral immunity, inflammatory reaction as well as hematopoiesis, and also play important roles in host-defense against infection and tumor growth. Abnormal levels of cytokines and growth factors have been shown to be associated with a variety of diseases. For instance, enhanced IL-1s levels have been reported to be related with sepsis, burn, and rheumatoid arthritis [1–4]. Enhanced erythropoietin (EPO) levels have been found in a series of diseases like certain forms of anemia, and tumors of the kidney or liver [5–7]. Therefore, the information of plasma levels of cytokines as well as growth factors may improve diagnosis, patient follow-up and selection of therapeutic treatments.
Databáze: OpenAIRE