Prediction and Validation of DXA-Derived Appendicular Fat-Free Adipose Tissue by a Single Ultrasound Image of the Forearm in Japanese Older Adults
| Autor: | Jeremy P. Loenneke, Robert S. Thiebaud, Eiji Fujita, Takuya Akamine, Takashi Abe, Mark Loftin |
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| Rok vydání: | 2017 |
| Předmět: |
animal structures
Radiological and Ultrasound Technology business.industry fungi Ultrasound Ulna Adipose tissue Anatomy 030204 cardiovascular system & hematology Stepwise regression musculoskeletal system 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Forearm medicine Lean body mass Radiology Nuclear Medicine and imaging 030212 general & internal medicine Subcutaneous adipose tissue business Nuclear medicine Ultrasound image |
| Zdroj: | Journal of Ultrasound in Medicine. 37:347-353 |
| ISSN: | 0278-4297 |
| Popis: | Objectives To develop regression-based equations for estimating dual-energy x-ray absorptiometry (DXA) derived appendicular fat-free adipose tissue (FFAT) using a single ultrasound image in the forearm, and to investigate the validity of those equations to calculate FFAT-free appendicular lean mass (aLM-minus-FFATappendicular) in 311 Japanese adults aged 60 to 79 years. Methods Subjects were randomly separated into two groups: 215 in the model-development group (91 men and 124 women) and 96 in the cross-validation group (42 men and 54 women). Appendicular fat mass and aLM were measured by the DXA, and subcutaneous adipose tissue (AT-forearm) and muscle (MT-ulna) thicknesses were measured by ultrasound. Appendicular FFAT was calculated based on the results of a previous study (appendicular FFAT = appendicular fat mass/0.85 x 0.15). The aLM was estimated from MT-ulna using a previously published equation (aLM = 4.89 x MT-ulna x body height – 9.15). Stepwise linear regression analysis was used to determine predictive models for DXA-derived appendicular FFAT from AT-forearm, sex, age, and anthropometrical variables. The best ultrasound prediction equation for estimation of appendicular FFAT was developed and then cross-validated in a subsample of older adults. Results There was no significant difference between the DXA-derived and ultrasound-predicted aLM-minus-FFATappendicular. A strong correlation was observed between the DXA-derived and ultrasound-predicted aLM-minus-FFATappendicular (r = 0.935, P |
| Databáze: | OpenAIRE |
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