randomized controlled study of intrathecal hyperbaric bupivacaine and hyperbaric bupivacaine with fentanyl in caesarean section, government medical college, Suryapet

Autor: Naik L Giridhar, Naik S Ravinder
Rok vydání: 2022
Předmět:
Zdroj: International journal of health sciences. :2210-2220
ISSN: 2550-696X
2550-6978
DOI: 10.53730/ijhs.v6ns5.9128
Popis: Background: Spinal anesthesia with hyperbaric bupivacaine and adjuvants such as Fentanyl is now the preferred technique for spinal anesthesia, and is the gold standard for caesarean section. The common procedure is to add such adjuvants in a two-syringe before intrathecal injection into hyperbaric bupivacaine. Drug mixing may alter anesthetic solution density and baricity and may change the distribution of medication in cerebrospinal fluid (CSF). Objectives: In this study, we aimed to assess the effect of comparing block characteristics, intraoperative hemodynamics, and postoperative pain relief in Caesarean section under the subarachnoid block (SAB), following administration of hyperbaric bupivacaine and Fentanyl as a mixture. Methods: The research population consisted of 100 patients parturient women undergoing elective caesarean section under spinal anesthesia with the age ranges aged 20-52 years. By using computer-generated random numbers to obtain they were allocated to one of the two classes of an evenly sized group (50 each). This is a forward-looking, comparative analysis using an inclusive protocol framework for similarly sized classes. Group A received intrathecally 2ml of 0.5% hyperbaric Bupivacaine (10 mg) and Group B received intrathecally 2ml of 0.5% hyperbaric Bupivacaine (10 mg) + 0.5ml of Fentanyl (25 μg) as a concurrent process.
Databáze: OpenAIRE