Early Predictive Biochemical, Electrocardiographic and Echocardiographic Markers for Cardiac Damage in Patients with Pulmonic Silicosis
| Autor: | Cristina Florescu, Elena Catalina Bica, Luciana Teodora Rotaru, Diana Rodica Tudoraşcu, Venera Cristina Dinescu, Ramona Constantina Vasile, Marius Gabriel Bunescu, Ileana Puiu, Nicoleta Cioatera, Florin Marius Romanescu, Roxana Edme Mustafa, Sorin Nicolae Dinescu |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Process equipment Materials Science (miscellaneous) Process Chemistry and Technology General Engineering General Chemistry General Medicine medicine.disease General Biochemistry Genetics and Molecular Biology Silicosis Internal medicine Materials Chemistry medicine Cardiology In patient General Pharmacology Toxicology and Pharmaceutics |
| Zdroj: | Revista de Chimie. 70:63-68 |
| ISSN: | 2668-8212 0034-7752 |
| DOI: | 10.37358/rc.19.1.6852 |
| Popis: | The aim of this study was to identify correlations between electrocardiographic and echocardiographic changes in patients with silicosis prior to the occurrence of chronic pulmonary heart disease. We conducted a prospective, descriptive, analytical study, in which we included a group of 67 patients consecutively admitted to the Health Promotion and Occupational Medicine Clinic between December 2016 and January 2018, aged 47 to 78 years.There was a biochemical and electrocardiographic evaluation for each patient as well as a right ventricle echocardiographic evaluation (diameters, volumes, function). A control group, including 25 patients with benign minor diseases that required a cardiologist consultation, was also used. From the electrocardiographic point of view, slight changes were observed regarding the waves of electrical activity of the right ventricle. Taking into account the degree of ventilatory dysfunction (depending on FEV1), changes in right heart echocardiographic parameters were identified. Thus, in what the most important right ventricular parameters, including the tricuspid annular plane systolic excursion (TAPSE) or the RV index of myocardial performance (RVMPI) were concerned, values at the upper limit of normality were recorded in most patients with moderate and severe ventilatory dysfunction. Values of echocardiographic parameters of the right heart at the upper limit of normality, correlated with the degree of ventilatory dysfunction, are early markers for cardiovascular damage in patients with pulmonary silicosis prior to the occurrence of chronic pulmonary heart disease also known ascor pulmonale. |
| Databáze: | OpenAIRE |
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