Gender differences in laboratory stress response among prescription opioid-dependent individuals
| Autor: | Francis Beylotte, Kathleen T. Brady, Andrew P. Teer, Sudie E. Back, Mary Ashley Mercer, Jenna L. McCauley |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Pharmacology
Drug medicine.medical_specialty business.industry media_common.quotation_subject Alcohol dependence Negative association Toxicology κ-opioid receptor Odds Fight-or-flight response Psychiatry and Mental health Prescription opioid Internal medicine Secondary analysis medicine Pharmacology (medical) business media_common |
| Zdroj: | Drug and Alcohol Dependence. 146:e199 |
| ISSN: | 0376-8716 |
| Popis: | s / Drug and Alcohol Dependence 146 (2015) e118–e201 e199 Conclusions: Heavy drinking is common among primary care patients who screen positive for drug use. One or more HDD was significantly associated with fewer days use of DOMC, and a higher odds of dependence and use of >1 drug at follow-up. The apparent negative association between HDD and days use of DOMC could be explained by the use of >1 drug, or by alcohol use as a replacement. These findings suggest that assessing for heavy drinking among drug users identified by screening in primary care may yield clinically useful information. Financial support: Secondary analysis of ASPIRE trial data, funded by NIDA 1 R01 DA025068 with support from SAMHSA. http://dx.doi.org/10.1016/j.drugalcdep.2014.09.455 Sex differences in depressive-like effects of kappa opioid receptor activation in rats Jazmine Mays, Dan Puttick, Shayla Russell, Elena Chartoff Psychiatry, Harvard Medical School, Belmont, MA |
| Databáze: | OpenAIRE |
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