The genetic aspects of berries: from field to health
| Autor: | Bruno Mezzetti, Massimiliano Gasparrini, José L. Quiles, José M. Alvarez-Suarez, Tamara Y. Forbes-Hernandez, Luca Mazzoni, Patricia Perez-Lopez, Francesca Giampieri, Maurizio Battino |
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| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
030109 nutrition & dietetics Nutrition and Dietetics business.industry Neurodegeneration Berry Cell cycle Biology Micronutrient medicine.disease Oxidative dna damage Biotechnology 03 medical and health sciences Biochemistry Phytochemical Polyphenol medicine business Agronomy and Crop Science Gene Food Science |
| Zdroj: | Journal of the Science of Food and Agriculture. 96:365-371 |
| ISSN: | 0022-5142 |
| DOI: | 10.1002/jsfa.7216 |
| Popis: | Berries are a relevant source of micronutrients and nonessential phytochemicals, such as polyphenol compounds, that play a synergistic and cumulative role in human health promotion. Several systematic analyses showed that berry phenolics are able to detoxify reactive oxygen and nitrogen species, blocking their production, to intervene in the cell cycle, participating in the transduction and expression of genes involved in apoptosis, and to repair oxidative DNA damage. As a consequence, the improvement of the nutritional quality of berries has become a new quality target of breeding and biotechnological strategies, to control or to increase the content of specific health-related compounds in fruits. This work reviews, on the basis of the in vitro and in vivo evidence, the main berries' phytochemical compounds and their possible mechanisms of action on pathways involved in several type of diseases, with particular attention to cancer, inflammation, neurodegeneration, diabetes and cardiovascular diseases. © 2015 Society of Chemical Industry |
| Databáze: | OpenAIRE |
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