Convenient method for the synthesis of C-phosphorylated N-arylformamidines

Autor:	Aleksandr A. Yurchenko, Aleksandr N. Kostyuk, Aleksandr M. Pinchuk, Anatoliy Marchenko, Georgyi Koidan, Anastasiya Hurieva, A. S. Merkulov
Rok vydání:	2010
Předmět:	Steric effects medicine.drug_class Stereochemistry Phosphorus Organic Chemistry chemistry.chemical_element Carboxamide Biochemistry Chemical synthesis Amidine chemistry.chemical_compound chemistry Drug Discovery Electronic effect Chemical reduction medicine Phosphorylation
Zdroj:	Tetrahedron. 66:3668-3677
ISSN:	0040-4020
Popis:	C -Phosphorylated (P V ) arylformamidines have been prepared by the reaction of N -arylamidotrichloromethyl derivatives of phosphorus, thiophosphorus, and selenophosphorus acids with secondary amines. Dependence of the reaction on the nature of chalcogene, electronic and steric factors has been studied. By reduction of N -arylformamidinophosphonoselenides the corresponding C -phosphorylated (P III ) arylformamidines have been synthesized.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9bb8b3b6e61b1d23b8fa5deb2aefe9ba https://doi.org/10.1016/j.tet.2010.03.087 Zobrazit plný text záznamu Full Text from ScienceDirect