Chlorination of 2,3,6-trialkyl-5,8-dihydroxy-1,4-naphthoquinones with HCl-MnO2 in acetic acid. effective transformation of 2,3,6-trialkyl-2,3,7-trichloro-1,2,3,4-tetrahydronaphthalene-1,4-diones into 7-chloro-2,3,6-trialkyl-5,8-dihydroxy-1,4-naphthoquinones

Autor:	V. A. Denisenko, N. S. Polonik, Sergey G. Polonik, V. F. Anufriev, O. P. Moiseenko
Rok vydání:	2011
Předmět:	Sodium dithionite chemistry.chemical_compound Acetic acid chemistry Stereochemistry Yield (chemistry) Organic Chemistry Chlorine chemistry.chemical_element Molecule Medicinal chemistry
Zdroj:	Russian Journal of Organic Chemistry. 47:1045-1049
ISSN:	1608-3393 1070-4280
Popis:	Chlorination of 2,3,6-trialkyl-5,8-dihydroxy-1,4-naphthoquinones with HCl-MnO2 in acetic acid gave a mixture of 7-chloro-2,3,6-trialkyl-5,8-dihydroxy-1,4-naphthoquinones and 2,3,7-trichloro-2,3,6-trialkyl-1,2,3,4-tetrahydronaphthalene-1,4-diones, the latter being formed via addition of the second chlorine molecule to monochloro derivatives. The reduction of 2,3,7-trichloro-2,3,6-trialkyl-1,2,3,4-tetrahydronaphthalene-1,4-diones with sodium dithionite in alkaline medium resulted in the formation of 7-chloro-2,3,6-trialkyl-5,8-dihydroxy-1,4-naphthoquinones in high yield.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9ba947e11baa4916dbd2570bfe840b54 https://doi.org/10.1134/s1070428011070128 Zobrazit plný text záznamu Plný text ve formátu PDF