Immunhistochemische Bestimmung von Östrogenrezeptoren in Mammakarzinomgeweben mittels monoclonaler Antikörper*
| Autor: | Stegner He, Maass H, Jonat W |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
Pathology
medicine.medical_specialty medicine.drug_class business.industry Endocrine therapy Obstetrics and Gynecology Estrogen receptor Monoclonal antibody medicine.disease Tumor tissue Breast cancer Maternity and Midwifery medicine Immunohistochemistry Breast carcinoma business Estrogen receptor assay |
| Zdroj: | Geburtshilfe und Frauenheilkunde. 45:473-476 |
| ISSN: | 1438-8804 0016-5751 |
| DOI: | 10.1055/s-2008-1036355 |
| Popis: | The results of preliminary investigations into specific immunohistochemical detection of the estrogen receptor in breast cancer tissue by means of monoclonal antibodies are presented. Thirty-one tumor tissue samples stored in a tumor tissue bank for between 10 and 35 months were immunohistochemically studied. The comparison between the immunohistochemical result and the result of the biochemical estrogen receptor assay show a large measure of agreement (90%). The comparison of the results with regard to response to endocrine therapy in cases of metastatization shows that immunohistochemical detection furnishes at least as much information as the dextran-coated charcoal method. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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