Abstract 2198: Rhythmic Risk in Idiopathic Dilated Cardiomyopathy Depending on the Evolution of Left Ventricular Ejection Fraction in Patients with Implantable Cardioverter Defibrillators
| Autor: | Claude Kouakam, Guillaume Theodore, Christelle Marquie, Didier Klug, Laurence Guedon-Moreau, François Brigadeau, Sylvestre Marechaux, Pascal de Groote, Dominique Lacroix, Salem Kacet |
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| Rok vydání: | 2007 |
| Předmět: | |
| Zdroj: | Circulation. 116 |
| ISSN: | 1524-4539 0009-7322 |
| DOI: | 10.1161/circ.116.suppl_16.ii_477-b |
| Popis: | Background : Patients with idiopathic dilated cardiomyopathy (DCM) receiving an ICD often improve their left ventricular dysfunction in the year following implantation due to reverse remodelling and/or optimization of concomitant drug therapy. We examined whether this improvement impacts the benefit of ICD in terms of appropriate therapy. Methods : The study comprised 93 consecutive DCM patients with LVEF 200 bpm or Results : Overall the mean LVEF increased by 7.2 % from 24.6±7% at baseline to 31.8±12% at revaluation. Two patterns were observed: 23 patients had a >14% LVEF increase (group 1) whereas 70 others had an increase Conclusions : In DCM, rhythmic risk is dynamic and inversely related to the improvement in LVEF. Reverse remodelling under optimal therapy is associated with a late favourable outcome, but 17% of these patients however benefit from ICD therapy in the early period. |
| Databáze: | OpenAIRE |
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